The biomaterials and nanomedicine group led by Prof. Yu Chen focuses on the development of versatile biomaterials and nanoplatforms for solving the critical issues of clinical biomedicine. The chosen nanoplatforms include mesoporous silica nanoparticles, mesoporous organosilica nanoparticles, magnetic nanoparticles, fluorescent nanoparticles, microbubbles, nanoliposomes, etc.
Our group also focuses on two-dimensional nanosheets and explore their broad biomedical applications, including 2D MXene, graphene, metal oxides, TMDCs, LDH, etc. In addition, some techniques such as 3D printing have been developed for the fabrication of 3D scaffolds and bio-implants for localized disease therapy and tissue engineering.
The broad biomedical applications of these biomaterials and nanoplatforms include drug/gene delivery, molecular imaging (MR imaging, CT, fluorescence imaging, PA imaging, US imaging, etc.), ultrasound therapy, photothermal therapy, nanocatalytic therapy, photodynamic therapy, and the fundamental research regarding the biological effects and biosafety of these nanoplatforms.